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1. Iptakalim alleviates rotenone-induced degeneration of Dopaminergic neurons through inhibiting microglia-mediated neuroinflammation SCIE SCOPUS PubMed

作者:Zhou, F; Wu, JY; Sun, XL; Yao, HH; Ding, JH; Hu, G

作者机构:[Zhou, F; Wu, JY; Sun, XL; Yao, HH; Ding, JH; Hu, G]Nanjing Med Univ, Dept Anat & Histol & Pharmacol, Neuropharmacol Lab, Nanjing 210029, Pe 更多

关键词:ATP-sensitive potassium channel; Iptakalim; Microglia; Neuroinflammation; Parkinson's disease; Rotenone

来源:NEUROPSYCHOPHARMACOLOGY,2007,Vol.32,Issue.12

WOS被引频次:49

Scopus被引频次:58

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q1

当年影响因子:6.157

最新一期影响因子:6.403

资源类型:外文期刊论文

2. ATP-sensitive potassium channel opener iptakalim protected against the cytotoxicity of MPP+ on SH-SY5Y cells by decreasing extracellular glutamate level SCIE SCOPUS PubMed

作者:Hu, LF; Wang, S; Shi, XR; Yao, HH; Sun, YH; Ding, JH; Liu, SY; Hu, G

作者机构:[Hu, LF; Wang, S; Shi, XR; Yao, HH; Sun, YH; Ding, JH; Liu, SY; Hu, G]Nanjing Med Univ, Dept Pharmacol, Lab Reprod Med & Neuropharmacol, 更多

关键词:Glutamate; Iptakalim; KATP channels; MPP+; Parkinson's disease; SH-SY5Y cell

来源:JOURNAL OF NEUROCHEMISTRY,2005,Vol.94,Issue.6

WOS被引频次:42

Scopus被引频次:45

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q1

当年影响因子:4.604

最新一期影响因子:4.083

资源类型:外文期刊论文

3. Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells SCIE SCOPUS PubMed

作者:Yang, Y; Liu, X; Ding, JH; Sun, J; Long, Y; Wang, F; Yao, HH; Hu, G

作者机构:[Yang, Y; Liu, X; Ding, JH; Sun, J; Long, Y; Wang, F; Yao, HH; Hu, G]Nanjing Med Univ, Dept Pharmacol & Neurobiol, Nanjing 210029, Peopl 更多

关键词:analysis of variance; ANOVA; ATP-sensitive potassium channels; DA; DAT; dopamine; dopamine transporter; K ATP; KCOs; mitochondrial K ATP channels; mitoK ATP; Parkinson's disease; PD; SNpc; substantia nigra pars compacta

来源:NEUROSCIENCE LETTERS,2004,Vol.366,Issue.1

WOS被引频次:27

Scopus被引频次:33

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q3

当年影响因子:2.019

最新一期影响因子:2.18

资源类型:外文期刊论文

4. Glibenclamide exerts an antitumor activity through reactive oxygen species-c-jun NH(2)-terminal kinase pathway in human gastric cancer cell tine MGC-803 PubMed SCIE SCOPUS

作者:Qian, X; Li, J; Ding, JH; Wang, ZY; Duan, L; Hu, G

作者机构:[Qian, Xia; Li, Jing; Ding, Jianhua; Wang, Zhiyuan; Duan, Lei; Hu, Gang] Nanjing Med Univ, Dept Pharmacol, Jiangsu 210029, Peoples R China.

关键词:Akt; C-jun NH(2)-terminal kinase; Glibenclamide; Human gastric cancer cell line MGC-803; Reactive oxygen species

来源:BIOCHEMICAL PHARMACOLOGY,2008,Vol.76,Issue.12

WOS被引频次:22

Scopus被引频次:31

ESI学科:PHARMACOLOGY & TOXICOLOGY

JCR分区:Q1

当年影响因子:4.838

最新一期影响因子:4.581

资源类型:外文期刊论文

5. K-ATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured Astrocytes PubMed SCIE SCOPUS

作者:Sun, XL; Zeng, XN; Zhou, F; Dai, CP; Ding, JH; Hu, G

作者机构:[Sun, Xiu-Lan; Zeng, Xiao-Ning; Zhou, Fang; Dai, Cui-Ping; Ding, Jian-Hua; Hu, Gang] Nanjing Med Univ, Dept Anat Histol & Pharmacol, Neuropharmacol La 更多

关键词:Glutamate uptake; Iptakalim; KATP channel opener; Mitochondria

来源:NEUROPSYCHOPHARMACOLOGY,2008,Vol.33,Issue.6

WOS被引频次:21

Scopus被引频次:32

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q1

当年影响因子:6.835

最新一期影响因子:6.403

资源类型:外文期刊论文

6. Metabolic inflammation exacerbates dopaminergic neuronal degeneration in response to acute MPTP challenge in type 2 diabetes mice SCIE SCOPUS PubMed

作者:Wang, L; Zhai, YQ; Xu, LL; Qiao, C; Sun, XL; Ding, JH; Lu, M; Hu, G

作者机构:[Wang, Ling; Zhai, Ying-Qi; Xu, Li-Li; Qiao, Chen; Sun, Xiu-Lan; Ding, Jian-Hua; Lu, Ming; Hu, Gang] Nanjing Med Univ, Dept Pharmacol, Jiangsu Key Lab 更多

关键词:α-Synuclein; ER stress; Metabolic inflammation; NLRP3 inflammasome; Parkinson's disease; Type 2 diabetes

来源:EXPERIMENTAL NEUROLOGY,2014,Vol.251

WOS被引频次:20

Scopus被引频次:43

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q1

当年影响因子:4.696

最新一期影响因子:4.706

资源类型:外文期刊论文

7. Effects of systemic administration of iptakalim on extracellular neurotransmitter levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats SCIE SCOPUS PubMed

作者:Wang, S; Hu, LF; Zhang, Y; Sun, T; Sun, YH; Liu, SY; Ding, JH; Wu, J; Hu, G

作者机构:[Wang, S; Hu, LF; Zhang, Y; Sun, T; Sun, YH; Liu, SY; Ding, JH; Wu, J; Hu, G]Nanjing Med Univ, Dept Pharmacol & Neurobiol, Nanjing 210 更多

关键词:6-hydroxydopamine; ATP-sensitive potassium channel; Glutamate uptake; Iptakalim; Neurotransmitter; Parkinson's disease

来源:NEUROPSYCHOPHARMACOLOGY,2006,Vol.31,Issue.5

WOS被引频次:20

Scopus被引频次:24

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q1

当年影响因子:5.889

最新一期影响因子:6.403

资源类型:外文期刊论文

8. The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells SCIE SCOPUS PubMed

作者:Liu, X; Wu, JY; Zhou, F; Sun, XL; Yao, HH; Yang, Y; Ding, JH; Hu, G

作者机构:[Liu, X; Wu, JY; Zhou, F; Sun, XL; Yao, HH; Yang, Y; Ding, JH; Hu, G]Nanjing Med Univ, Lab Neuropharmacol, Dept Anat Histol & Pharmacol, 更多

关键词:BV-2 cell; Iptakalim; Mitochondrial ATP-sensitive potassium channel (mitoKATP channel); Parkinson's disease

来源:NEUROSCIENCE LETTERS,2006,Vol.394,Issue.2

WOS被引频次:20

Scopus被引频次:26

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q3

当年影响因子:2.092

最新一期影响因子:2.18

资源类型:外文期刊论文

9. Iptakalim hydrochloride protects cells against neurotoxin-induced glutamate transporter dysfunction in in vitro and in vivo models PubMed SCIE SCOPUS

作者:Yang, YL; Meng, CH; Ding, JH; He, HR; Ellsworth, K; Wu, J; Hu, G

作者机构:[Yang, YL; Meng, CH; Ding, JH; He, HR; Ellsworth, K; Wu, J; Hu, G]St Josephs Hosp, Barrow Neurol Inst, Div Neurol, Neurophysiol Lab,, Phoe 更多

关键词:ATP-sensitive potassium channel; Glutamate transporter; Glutamate uptake; Iptakalim hydrochloride; Neuroprotection; Parkinson's disease

来源:BRAIN RESEARCH,2005,Vol.1049,Issue.1

WOS被引频次:16

Scopus被引频次:19

ESI学科:NEUROSCIENCE & BEHAVIOR

JCR分区:Q3

当年影响因子:2.296

最新一期影响因子:2.746

资源类型:外文期刊论文

12. d-Serine Regulates Proliferation and Neuronal Differentiation of Neural Stem Cells from Postnatal Mouse Forebrain SCIE SCOPUS PubMed

作者:Huang, X; Kong, H; Tang, M; Lu, M; Ding, JH; Hu, G

作者机构:[Huang, Xu; Kong, Hui; Tang, Mi; Lu, Ming; Ding, Jian-Hua; Hu, Gang] Nanjing Med Univ, Jiangsu Key Lab Neurodegenerat, Dept Pharmacol, Nanjing 210029, 更多

关键词:d-Serine; Differentiation; N-methyl-d-aspartate; Neural stem cell; Proliferation

来源:CNS NEUROSCIENCE & THERAPEUTICS,2012,Vol.18,Issue.1

WOS被引频次:10

Scopus被引频次:19

ESI学科:PHARMACOLOGY & TOXICOLOGY

JCR分区:Q1

当年影响因子:4.458

最新一期影响因子:3.919

资源类型:外文期刊论文

13. 埃他卡林通过上调Kir6.1和Kir6.2 mRNA表达抑制可卡因激发诱导的大鼠纹状体和伏隔核多巴胺水平的增加(英文) 知网 SCIE SCOPUS PubMed

作者:刘昀;何海蓉;丁建花;顾兵;汪海;胡刚

作者机构:[刘昀]南京医科大学药理学与神经生物学系,军事医学科学院毒物药物研究所,南京医科大学药理学与神经生物学系 南京 210029 中国,南京 210029 中国,北京 100850 中国 更多

来源:Acta Pharmacologica Sinica,2003,Vol. 24,Issue. 6

关键词:ATP-sensitive potassium channel opener; ATP-sensitive potassium channel subunits; Dopamine; Gene expression regulation; Glutamates; Iptkalim; Messenger RNA

年份:2003

资源类型:中文期刊论文;外文期刊论文

14. Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis PubMed SCIE SCOPUS

作者:Lu, M; Yang, JZ; Geng, F; Ding, JH; Hu, G

作者机构:[Lu, Ming; Yang, Jing-Zhe; Geng, Fan; Ding, Jian-Hua; Hu, Gang] Nanjing Med Univ, Dept Pharmacol, Jiangsu Key Lab Neurodegenerat, Nanjing 210029, Jian 更多

关键词:Chronic mild stress; hippocampal neurogenesis; Iptakalim; major depression; neuro-inflammation

来源:INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY,2014,Vol.17,Issue.9

WOS被引频次:8

Scopus被引频次:32

ESI学科:PSYCHIATRY/PSYCHOLOGY

JCR分区:Q1

当年影响因子:4.009

最新一期影响因子:4.712

资源类型:外文期刊论文

15. Inhibitory effects of 1-methyl-4-phenylpyridinium on glutamate uptake into cultured C6 glioma cells SCIE SCOPUS PubMed

作者:Yao, HH; Ding, JH; He, HR; Hu, G

作者机构:[Yao, HH; Ding, JH; He, HR; Hu, G]Nanjing Med Univ, Dept Pharmacol & Neurobiol, Nanjing 210029, Peoples R China.

关键词:1-methyl-4-phenylpyridinium; 4-O-methyl-12-O-tetradecanoylphorbol-13-acetate; Apoptosis; Glioma; Glutamate acid

来源:ACTA PHARMACOLOGICA SINICA,2004,Vol.25,Issue.7

WOS被引频次:6

Scopus被引频次:6

ESI学科:PHARMACOLOGY & TOXICOLOGY

JCR分区:Q2

当年影响因子:1.125

最新一期影响因子:3.223

资源类型:外文期刊论文

20. Kir6.2 Deficiency Promotes Mesencephalic Neural Precursor Cell Differentiation via Regulating miR-133b/GDNF in a Parkinson's Disease Mouse Model PubMed SCOPUS SCIE

作者:<a href='http://ir.njmu.edu.cn/widgets/sdjgk/?h=scholar&job=org&a_id=239458' class='f_htr_a' target='_blank'>Zhou, Y</a>; Zhu, JL; Lv, Y; Song, CH; Ding, JH;<a href='http://ir.njmu.edu.cn/widgets/sdjgk/?h=scholar&job=org&a_id=240059' class='f_htr_a' target='_blank'> Xiao, M</a>;<a href='javascript:void(0)' onclick='zhuozhe(153425,1397928,event)' class='beiyingpinci' target='_self'> Lu, M</a>; Hu, G

作者机构:[Zhou, Yan; Zhu, Jialei; Lv, Yang; Song, Chenghuan; Ding, Jianhua; Xiao, Ming; Lu, Ming; Hu, Gang] Nanjing Med Univ, Dept Pharmacol, Jiangsu Key Lab N 更多

关键词:Adult neurogenesis; Differentiation; Kir6.2/K-ATP; miR-133b; Nurr1+ precursors; Parkinson’s disease

来源:MOLECULAR NEUROBIOLOGY,2018,Vol.55,Issue.11

ESI学科:NEUROSCIENCE & BEHAVIOR

最新一期影响因子:6.19

资源类型:外文期刊论文

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